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American Journal of Epidemiology Vol. 144, No. 7: 716
Copyright © 1996 by The Johns Hopkins University School of Hygiene and Public Health

correction

ERRATUM

ABSTRACT

Dr. Dieter Flesch-Janys et al. have informed the Journal that some of the results published in their paper on polychlorinated dioxins and furans (PCDD/F) and mortality in German workers from a herbicide-producing plant (1) contain a computational error. It was detected while preparing new data analyses in collaboration with Dr. H. Becher and Dr. K. Steindorf of the German Cancer Research Center, Heidelberg, Germany, who also computed the corrected estimates. The error had occurred in the computation of the time between birth and the end of observation for the PCDD/F-exposed cohort of chemical workers (the old follow-up date, December 31, 1989, was used instead of the new one, December 31, 1992). The error affected the estimated relative risks using an unexposed cohort of workers as the reference group (tables 3 and 4 in the originally published paper). The relative risk estimates for the internal comparison (tables 5-7) remain substantially unchanged.

The corrected estimates for table 4 of the original paper are presented in the accompanying table.

The corrected relative risk estimates are slightly lower than those originally reported. Thus, some confidence intervals in the lower dose regions now include one. However, the pattern of the dose-response relations for total and cancer mortality remains unchanged, and the trend tests still are significant. For mortality due to ischemic heart diseases, a numeric increase now is first observed for the subgroup of toxic equivalencies of polychlorinated dibenzo-p-dioxins and -furans (TOTTEQ) with more than 278 ng/kg of blood fat.

The conclusion of the paper, "the results of this cohort study support the hypothesis of a dose-related effect of PCDD/F on cancer and ischemic heart diseases mortality" (1, p. 1174), remains unaffected.

A corrected version of the paper can be requested from Dr. D. Flesch-Janys, Medical Center for Chemical Workers' Health, Fuhlsbuttler Str. 401, D-22309 Hamburg, Germany.

The Journal regrets this computational error and apologizes for any inconvenience this may have caused readers.


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