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Am J Epidemiol 2003; 158:404-405.
Copyright © 2003 by Johns Hopkins Bloomberg School of Public Health

ORIGINAL CONTRIBUTIONS

Lee Responds to "Testing for Hardy-Weinberg Disequilibrium"

Wen-Chung Lee 

From the Graduate Institute of Epidemiology, College of Public Health, National Taiwan University, Taipei, Taiwan.

Received for publication April 28, 2003; accepted for publication May 8, 2003.

Abbreviations: Abbreviation: HWT, Hardy-Weinberg disequilibrium test.

The first 10% of the full text of this article appears below.

I appreciate Weinberg and Morris’ thoughtful commentary (1) on my paper (2). In their article, they put my work under the perspective of gene mapping in the postgenomic era. I share the same view with them that the method proposed in my paper amounts to a tree-shaking approach to harvesting the high-hanging fruit (a low-cost approach to generating hypotheses aimed at localizing disease-susceptibility . . . [Full Text of this Article]


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Related articles in Am. J. Epidemiol.:

Searching for Disease-Susceptibility Loci by Testing for Hardy-Weinberg Disequilibrium in a Gene Bank of Affected Individuals
Wen-Chung Lee
Am. J. Epidemiol. 2003 158: 397-400. [Abstract] [FREE Full Text]  

Invited Commentary: Testing for Hardy-Weinberg Disequilibrium Using a Genome Single-Nucleotide Polymorphism Scan Based on Cases Only
Clarice R. Weinberg and Richard W. Morris
Am. J. Epidemiol. 2003 158: 401-403. [Extract] [FREE Full Text]  



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