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American Journal of Epidemiology 2005 161(1):36-37; doi:10.1093/aje/kwi004
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Copyright © 2005 by the Johns Hopkins Bloomberg School of Public Health

ORIGINAL CONTRIBUTIONS

Tu et al. Respond to "Barker Meets Simpson"

Yu-Kang Tu1,2 , George T. H. Ellison3, Robert West1 and Mark S. Gilthorpe1

1 Biostatistics Unit, Centre for Epidemiology and Biostatistics, University of Leeds, Leeds, United Kingdom.
2 Leeds Dental Institute, University of Leeds, Leeds, United Kingdom.
3 St. George’s Hospital Medical School, London, United Kingdom.

Received for publication September 22, 2004; accepted for publication September 28, 2004.

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Weinberg (1) highlights the challenges and pitfalls faced when statistically analyzing data from observational (nonrandomized) studies to explore causal hypotheses. She reminds us that statistically significant associations between variables in such studies can be ambiguous. Extreme caution is required when statistical modeling of data from observational studies is used to infer causality from statistical associations between exposure and outcome variables. When knowledge . . . [Full Text of this Article]


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Y.-K. Tu, G. T. H. Ellison, R. M. West, and M. S. Gilthorpe
TU ET AL. REPLY
Am. J. Epidemiol., August 1, 2005; 162(3): 293 - 293.
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M. W. Gillman
RE: "WHY EVIDENCE FOR THE FETAL ORIGINS OF ADULT DISEASE MIGHT BE A STATISTICAL ARTIFACT: THE 'REVERSAL PARADOX' FOR THE RELATION BETWEEN BIRTH WEIGHT AND BLOOD PRESSURE IN LATER LIFE"
Am. J. Epidemiol., August 1, 2005; 162(3): 292 - 292.
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