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Am J Epidemiol 2004; 159:872-881.
Copyright © 2004 by the Johns Hopkins Bloomberg School of Public Health


ORIGINAL CONTRIBUTIONS

Neonatal Outcome following Maternal Antenatal Depression and Anxiety: A Population-based Study

Liselott Andersson1,2 , Inger Sundström-Poromaa3, Marianne Wulff1, Monica Åström4 and Marie Bixo1

1 Department of Clinical Sciences, Division of Obstetrics and Gynecology, Umeå University, Umeå, Sweden.
2 Department of Obstetrics and Gynecology, Sunderby Hospital, Luleå, Sweden.
3 Department of Women’s and Children’s Health, University Hospital, Uppsala, Sweden.
4 Department of Clinical Sciences, Division of Psychiatry, Umeå University, Umeå, Sweden.

The aim of this study was to determine neonatal outcomes among women who had depressive and anxiety disorders during the second trimester of pregnancy in a population-based sample. Participants were 1,465 women and their neonates born at two obstetric clinics in Sweden. The inclusion period for the women was October 2, 2000–October 1, 2001. The Primary Care Evaluation of Mental Disorders (PRIME-MD) classification system was used to evaluate mental disorders in the second trimester of pregnancy. For assessment of demographic characteristics, birth statistics, and birth-related complications, the medical records of the included women and their offspring were reviewed after delivery. The study results revealed no differences in neonatal outcome between women with antenatal depressive disorders and/or anxiety disorders and healthy subjects. The authors conclude that neonatal outcome did not deteriorate despite the women’s impaired mental health during pregnancy.

anxiety; depression; pregnancy

Abbreviations: Abbreviations: CI, confidence interval; CES-D [Scale], Center for Epidemiologic Studies Depression [Scale]; DSM-IV, Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition; OR, odds ratio; PRIME-MD, Primary Care Evaluation of Mental Disorders.


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